Triboelectric nanogenerators (TENGs) are promising mechanical energy harvesters. However, they suffer from intrinsically low output current (μA) and power (μW–mW), limiting their practical application. This paper presents an origami-structured ultrahigh-performance TENG (OU-TENG) with directed charge polarization and enhanced discharge, enabled by high-voltage diodes and vertical and lateral discharge channels. This structure can produce dual amplified peaks within a single folding–unfolding cycle, achieving ultrahigh outputs of 2000 V, 8   A, and 4600   W. The corresponding peak voltage, current, and power densities are 276   kV/m², 1107   A/m², and 636   kW/m², respectively. Systematic analysis revealed that the output performance was affected by the charge-inducing layer material, discharge channel geometry, diode direction, device size, and number of stacked layers. The ultrahigh output capability was demonstrated by the real-time illumination of 3,000 LEDs, 50-W commercial LED bulbs, and 108-W commercial fluorescent lamps, and the continuous operation of commercial sensors. Furthermore, OU-TENG was integrated with the human body to harvest biomechanical energy from walking, jumping, and squatting motions, achieving voltages exceeding 2   kV and currents above 5   A. In summary, this study established a strategy to overcome the output limitations of conventional TENGs, highlighting the potential of OU-TENG as a practical ultrahigh-output energy harvester.