Ti:WS2 films with duplex-layer structure were deposited by magnetron sputtering. The mechanical properties and tribological performance of Ti:WS2 film were improved after Ti incorporation. Ti:WS2/P201 hybrid system constructed by combination of Ti:WS2 film and P201 oil displays a synergistic lubricating effect, significantly prolonging lubricating lifetime compared to the single film. It is attributed to the effectively repairing function in some wear areas owing to the debris acted as an additive in oil. However, the AO irradiation can decrease the tribological performance of Ti:WS2/P201 hybrid system to different extent, depending on dose of irradiation. The high-dose AO irradiation rapidly deteriorates the tribological properties of the hybrid system, dramatically shortening the lubricating lifetime. It is found that the AO irradiated oil caused the severe tribo-oxidation re-action with the increase of sliding distance, resulting in forming numerous W oxides and carbide. Finally, failure mechanism of Ti:WS2/P201 hybrid system under AO irradiation were revealed.