From daily intuitions to sophisticated atomic-scale experiments, friction is usually found to increase with normal load. Using first-principle calculations, here we show that the sliding friction of a graphene/graphene system can decrease with increasing normal load and collapse to nearly zero at a critical point. The unusual collapse of friction is attributed to an abnormal transition of the sliding potential energy surface from corrugated, to substantially flattened, and eventually to counter-corrugated states. The energy dissipation during the mutual sliding is thus suppressed sufficiently under the critical pressure. The friction collapse behavior is reproducible for other sliding systems, such as Xe/Cu, Pd/graphite, and MoS2/MoS2, suggesting its universality. The proposed mechanism for diminishing energy corrugation under critical normal load, added to the traditional structural lubricity, enriches our fundamental understanding about superlubricity and isostructural phase transitions and offers a novel means of achieving nearly frictionless sliding interfaces.